Metronidazole has demonstrated proof of mutagenic activity in many in vitro bacterial assay devices. Also, a dose-response increase in the frequency of micronuclei was observed in mice right after intraperitoneal injections and a rise in chromosome aberrations happen to be claimed in patients with Crohn's condition who were being dealt with with two hundred-1200 mg/working day of metronidazole for one to 24 months.
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